What is HiPP PRE Bio Combiotik?
HiPP PRE Bio Combiotik is a German organic infant formula suitable from birth, made from organic skimmed milk and organic whey, with lactose as its only carbohydrate and no starch. One box is 600 g — about 153 fl oz of prepared formula, roughly 30 bottles of 5 oz.
What separates the German HiPP line from almost every other European baby formula on the shelf is that it carries both halves of the gut story. Most organic baby formula adds a prebiotic fibre and stops there. HiPP's Combiotik recipe pairs GOS prebiotic fibre, made from the formula's own lactose, with a live probiotic culture — Lactobacillus fermentum hereditum, a lactic acid culture originally found in breast milk.
PRE is HiPP's starter tier, labelled von Geburt an — from birth. The German box also calls it ideal zum Zufüttern, ideal for topping up, which is why so many parents reach for it when they are combination feeding: breastfeeding, and finishing with a bottle. Its carbohydrate is lactose only, with no starch, so it stays thin and light rather than filling.
It is EU Organic certified, made in Germany by HiPP under the organic control code DE-ÖKO-001. It is not Demeter certified — that is Holle's tier, not HiPP's, and we would rather say so than let you assume it.
0+ moSuitable from birth
600 gOne German box
~153 fl oz≈ 30 × 5 oz bottles
EU OrganicDE-ÖKO-001 · Germany
What's in HiPP PRE Bio Combiotik per 100ml?
Prepared as directed, every 100ml of HiPP PRE Bio Combiotik provides 66 kcal, 1.25 g protein and 51 mg calcium, with 0 g starch — the carbohydrate is lactose only. The prebiotic is GOS made from lactose, the probiotic is the live culture Lactobacillus fermentum hereditum, and the long-chain fats come from fish oil and Mortierella alpina oil, supplying DHA and ARA.
| Per 100ml prepared | Amount |
|---|---|
| Energy | 66 kcal |
| Protein | 1.25 g |
| Calcium | 51 mg |
| Starch | 0 g |
| Carbohydrate source | Lactose only |
| Prebiotic | GOS (from lactose) |
| Probiotic culture | L. fermentum hereditum |
| DHA source | Fish oil |
| ARA source | M. alpina oil |
| Folate form | Metafolin |
Figures are per 100ml of prepared formula, from HiPP's published data for the German 600 g box. Fat and total carbohydrate in grams are not published for this stage — read the panel on your own box for the full table.
What does Combiotik mean in HiPP PRE Bio Combiotik?
Combiotik is HiPP's name for putting a prebiotic and a probiotic in the same box. The prebiotic is GOS — galacto-oligosaccharide fibre made from the formula's own lactose. The probiotic is Lactobacillus fermentum hereditum, a live lactic acid culture originally found in breast milk. The fibre is the food; the culture is the organism that feeds on it.
Most organic European formula carries one or the other. Holle's PRE adds neither. Kendamil adds GOS but no live culture. HiPP's German Bio Combiotik line is the one in this catalogue that carries both — and that pairing, rather than the organic certificate that plenty of brands share, is the honest reason to choose it.
A word on what this does not mean. Prebiotic fibre and live cultures are not a treatment for colic, reflux or a diagnosed allergy, and no formula should be sold as one. If your baby has a medical feeding problem, ask your paediatrician about a hydrolysed or specialist formula instead.
GOS prebiotic · the fibre
L. fermentum hereditum · the live culture
Illustrations are schematic and not to scale. GOS is a chain of galactose units made from the formula's own lactose; L. fermentum hereditum is a rod-shaped lactic acid bacterium.
What is not in HiPP PRE Bio Combiotik?
There is no starch, no maltodextrin and no corn syrup in HiPP PRE — the only carbohydrate is lactose, the same sugar that dominates breast milk — and it is free from soy. Being straight about the other side: it does contain palm oil, from certified sustainable sources, and its DHA comes from fish oil rather than algae.
- No starch
- No maltodextrin
- No corn syrup
- No soy
- No added sugar
- Lactose-only carbohydrate
How does HiPP PRE Bio Combiotik compare to Holle PRE and Kendamil Organic Stage 1?
HiPP PRE is the only one of the three with a live probiotic culture alongside its prebiotic fibre. Holle PRE is the only one that is Demeter biodynamic certified. Kendamil Organic Stage 1 is the only one with a whole-milk base, no palm oil and vegetarian algae DHA. All three are organic certified and all three are lactose-led.
| From birth · starter stage | HiPP PRE | Holle PRE | Kendamil Organic 1 |
|---|---|---|---|
| Organic certified | EU Organic | EU Organic + Demeter | EU / UK Organic |
| Milk base | Skimmed milk + whey | Skimmed milk + whey | Whole + skimmed milk |
| Protein / 100ml | 1.25 g | See product page | 1.4 g |
| Carbohydrate | Lactose only | Lactose only | Lactose (6.5 g of 7 g) |
| Palm oil | Yes | Yes | No |
| DHA source | Fish oil | Microalgae | Microalgae |
| Probiotic culture | L. fermentum hereditum | None | None |
| Prebiotic | GOS | None stated | GOS |
| Pack size | 600 g box | 400 g box | 800 g tin |
Being straight with you: if a stricter-than-organic certificate is what matters to you, Holle PRE is the better box — it is Demeter biodynamic and HiPP is not. If you are avoiding palm oil, or you want DHA from algae rather than fish, Kendamil Organic Stage 1 is the better tin. We stock both. Note that the three packs are different sizes — 600 g here, 400 g for Holle, 800 g for Kendamil — so compare price per prepared ounce, not price per pack. HiPP PRE's real advantage is the Combiotik pairing and the starch-free, lactose-only recipe.
How many boxes of formula will my baby need per month?
One 600 g box of HiPP PRE makes about 153 fl oz of prepared formula, roughly 30 bottles of 5 oz. A newborn taking PRE as their only feed works through about 6 to 8 boxes a month once feeding volumes settle; in the first three to four weeks, around 2 boxes is typical.
Those figures assume PRE is doing all the work. Many parents use it the way HiPP intends — as a top-up alongside breastfeeding — and in that case a box lasts considerably longer. Buy a few weeks at a time until you know your own baby's pattern, then stock up.
Estimates for exclusive formula feeding. Every baby feeds differently — use these for planning, not as a target.
How do you prepare HiPP PRE Bio Combiotik?
Sterilise the bottle, boil fresh water and let it cool to 40–50°C, pour the measured water in first, then add one level scoop (about 4.3 g) for every 30ml of water, shake for about 15 seconds, cool to around 37°C, test a drop on your wrist, and discard anything left one hour after your baby starts drinking.
40–50°CWater temperature
1 : 30mlOne level scoop per 30ml
4.3 gScoop size in this box
1 hourDiscard after feeding starts
1
Sterilise everything
Wash your hands, then sterilise the bottle, teat, cap and ring before every single feed.
2
Boil and cool the water
Boil fresh drinking water, then let it cool to 40–50°C (104–122°F), the temperature HiPP's own label specifies.
3
Water into the bottle first
Pour the measured water into the sterilised bottle before you add any powder — never the other way round.
4
Add level scoops
Add one level scoop — about 4.3 g — for every 30ml of water, levelling each scoop against the edge of the box. Never heap them.
5
Cap and shake
Close the bottle and shake for about 15 seconds, until no powder is left clinging to the sides.
6
Cool, test, feed
Cool to about 37°C (98.6°F), test a drop on the inside of your wrist, and discard anything left one hour after your baby starts drinking.
Never use artificially softened water or water that has been boiled more than once. Prepare a fresh bottle for every feed, never reheat, never microwave, and discard anything left one hour after your baby starts drinking.
A note on water temperature. HiPP specifies water at about 40–50°C for this formula, and that is the instruction printed on your box. It is set deliberately — hotter water damages the live cultures and heat-sensitive vitamins this formula is built around.
Many health authorities, including the NHS and WHO, advise 70°C or hotter for any powdered formula, because powder is not sterile and that temperature kills bacteria that can occasionally be present. The difference matters most for newborns, premature babies, and babies with weakened immunity. If your baby is in one of those groups, ask your paediatrician or health visitor which to follow for your situation.
A note on water temperature. HiPP specifies water at about 40–50°C for this formula, and that is the instruction printed on your box. It is set deliberately — hotter water damages the live cultures and heat-sensitive vitamins this formula is built around.
Many health authorities, including the NHS and WHO, advise 70°C or hotter for any powdered formula, because powder is not sterile and that temperature kills bacteria that can occasionally be present. The difference matters most for newborns, premature babies, and babies with weakened immunity. If your baby is in one of those groups, ask your paediatrician or health visitor which to follow for your situation.
Please read before buying
HiPP PRE contains cow's milk protein, lactose and fish oil. It is not suitable for babies with a diagnosed cow's milk protein allergy or a fish allergy, and it is not a hypoallergenic formula. Breastfeeding is best for your baby — talk to your health visitor or doctor before starting or changing a formula.
Store boxes in a cool, dry place. Once opened, use within about three weeks. Never reheat or microwave prepared formula.
PRE or Stage 1?
HiPP labels PRE ideal zum Zufüttern — ideal for topping up alongside breastfeeding — and Stage 1 gut sättigend, well-filling. Both are suitable from birth. If your baby is exclusively bottle-fed and seems hungry again soon after a feed, HiPP Stage 1 is the more filling of the two.
HiPP PRE Bio Combiotik: frequently asked questions
Is HiPP PRE suitable from birth?
Yes. The German box states von Geburt an — from birth — and PRE is HiPP's starter tier, the stage closest in composition to breast milk. If you have seen this product listed anywhere as a 6+ month formula, including previously on this page, that was an error and it has been corrected. PRE is a newborn formula.
What is the difference between HiPP PRE and HiPP Stage 1?
Both are suitable from birth. PRE is lactose-only with no starch, so it is thinner and lighter, and HiPP describes it as ideal for topping up alongside breastfeeding. Stage 1 contains organic starch, which HiPP labels gut sättigend — well-filling — and positions as the standalone first infant milk for babies who are not breastfed.
Can I use HiPP PRE alongside breastfeeding?
Yes, and that is precisely the use HiPP designed it for. The German label calls it ideal for supplementary feeding. Many parents breastfeed and offer a bottle of PRE for one or two feeds a day. Breast milk remains the best food for your baby, so speak to your health visitor or doctor before you begin combination feeding.
Does HiPP PRE contain starch or maltodextrin?
No to both. HiPP PRE's carbohydrate is lactose only — the ingredient panel lists 0 g starch — and there is no maltodextrin and no corn syrup. That is unusual even among organic formulas: HiPP's own Stage 1, Stage 2 and Stage 3 all contain organic starch, and Holle's German range uses maltodextrin.
Is HiPP PRE Demeter certified?
No. HiPP PRE is EU Organic certified and carries the German organic control code DE-ÖKO-001, but it is not Demeter. Demeter is a biodynamic standard stricter than EU Organic, and in this catalogue it belongs to parts of the Holle range. If Demeter is what you are after, Holle PRE is the box to buy and we stock it.
How many bottles does one 600 g box of HiPP PRE make?
About 153 fl oz of prepared formula, which is roughly 30 bottles of 5 oz, using the standard ratio of one level scoop to every 30ml of water. Actual bottles depend on the size of your baby's feeds — a newborn on 2 to 3 oz feeds will get considerably more bottles out of a box than a three-month-old on 6 oz.
When should we move on from HiPP PRE?
PRE can be used for the whole first six months. Many parents switch to HiPP Stage 1 earlier, once a baby is exclusively bottle-fed and seems hungry soon after feeds, because Stage 1 is the more filling of the two. After six months the follow-on stage is HiPP Stage 2. There is no rush and no need to change while PRE is working.
Related formulas at Bonpek Baby
- HiPP Stage 1 (German)The more filling from-birth option in the same German Combiotik line.
- HiPP Stage 2 (German)The follow-on milk from six months, when solids begin.
- Holle PREThe Demeter biodynamic alternative at the same stage, in a 400 g box.
- Kendamil Organic Stage 1Whole-milk base, no palm oil and algae DHA, in an 800 g tin.
- HiPP HA PREHiPP's hydrolysed starter milk — discuss it with your paediatrician first.
- All baby formulasBrowse every European formula we stock, by brand and stage.
Why parents buy from Bonpek Baby
- Authentic from Europe for 8+ years
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Product information last reviewed by the Bonpek Baby team in September 2026 against the manufacturer's current published ingredient and nutrition data. Always check the label on your tin, as manufacturers reformulate from time to time.
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